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Research Area A

mRNA Biosynthesis

A01

Transcript quality effects of RNAPII speed variation
Go to Project A01
A02
Maintaining gene expression fidelity in response to DNA- and RNA-protein crosslinks
Go to Project A02

A03

The role of chromatin structure regulation in the susceptibility to transcription-blocking lesions
Go to Project A03

A04

Consequences of age-related G-quadruplex formation for the fidelity of mammalian transcription
Go to Project A04

A05

Regulation of splicing fidelity in response to DNA double-strand breaks
Go to Project A05

A06

Regulation of alternative polyadenylation by RNA-binding proteins in senescence
Go to Project A06

A07

Speed vs. fidelity: The role of nuclear RNA export under cellular stress
Go to Project A07

A08

Impact of nonsense-mediated mRNA decay on gene expression fidelity
Institute for Genetics, University of Cologne
Go to Project A08

Research Area B

Protein Biosynthesis

B01

Clearance of defective mRNA by-products by the ribosome-associated quality control pathway in stress and disease
Go to Project B01

B02

Coordination of endoplasmic reticulum-associated fidelity machines
Go to Project B02

B03

Stress-dependent regulation of organellar proteome plasticity by dynamic selection of different translation initiation sites
Go to Project B03

B04

Chronic stress-associated alterations of translation fidelity
Go to Project B04

B05

Predicting the impact of biosynthetic fidelity on protein folding
Go to Project B05

B06

Defining the interplay between RNA and protein toxicity in C9orf72-related amyotrophic lateral sclerosis
Go to Project B06

B07

Protein targeting and safeguarding upon oxidative unfolding stress
Go to Project B07

B08

Metabolic signaling as a safeguard of translational fidelity
Go to Project B08

Central Projects C

Central Projects

CP01

Administration, communication, dissemination
Go to Project CP01

CP02

Quantitative Proteomics
Go to Project CP02

INF

Information Infrastructure Project: Scientific data management and data analytics
Go to INF

IRTG

Integrated Research Training Group
Go to IRTG