CRC 1678
Publications
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2026
Alarcon R, Köster D, Behrmann S, Ignatova Z (2026). ADAM-tRNA-seq: an optimized approach for demultiplexing and enhanced hierarchal mapping in direct tRNA sequencing. Nucleic Acids Res. Jan 22;54(3):gkag022. DOI: 10.1093/nar/gkag022
da Silva PFL, Ropert B, Rieckher M, Rive C, Schumacher B (2026). Neuronal DNA repair mediates systemic mitochondrial maintenance through acetylcholine signaling. bioRxiv 2026.02.11.705232. DOI: 10.64898/2026.02.11.705232
Faehling T, Reiff T, Schumacher B, Arndt R, Amatruda JF, Grünewald TGP, Cidre-Aranaz F (2026). Beyond the mouse: 3R-guided alternative animal models transforming cancer research. Mol Cancer. Mar 26. DOI: 10.1186/s12943-026-02601-0
Gallrein C, Meyer DH, Woitzat Y, Ramirez-Ramirez V, Vuong-Brender T, Kirstein J, Schumacher B (2026). Aging clocks delineate neuron types vulnerable or resilient to neurodegeneration and identify neuroprotective interventions. Nat Aging. DOI: 10.1038/s43587-026-01067-5
Köhler D, Kleinenkuhnen N, Rastegar K, Baar T, Nikopoulou C, Kondylis V, Milchevskaya V, Schmid M, Tessarz P, Tresch A (2026). A spectral dimension reduction technique that improves pattern detection in multivariate spatial data. Bioinformatics. Jan 31:btag052. DOI: 10.1093/bioinformatics/btag052
Kueckelmann S, Theunissen S, Meyer Zu Altenschildesche F, von Ondarza L, Lackmann JW, Franitza M, Becker K, Boehm V, Gehring NH (2026). SMG1:SMG8:SMG9-complex integrity supports efficient execution of nonsense-mediated mRNA decay. Nucleic Acids Res. Feb 24;54(5):gkag193. DOI: 10.1093/nar/gkag193
Kurscheidt K, Theunissen S, Pasquali N, Becker K, Boehm V, Conti E, Gehring NH (2026). Composite SMG5-SMG6 PIN domain formation is essential for NMD. Nat Commun. Feb 19;17(1):1934. DOI: 10.1038/s41467-026-69819-w
Nabawi Y, Doğan C, Petrović D, Perçin G, Koyuncu S, Vilchez D (2026). Proteostasis of organelles in aging and disease. FEBS J. Feb 4. DOI: 10.1111/febs.70439
2025
Audebert L, Allen GE, Chen S, Panasenko OO, Huch S, Polte C, Ignatova Z, Pelechano V, Collart MA (2025) Puf3 contributes to changes in mRNA solubility, translation elongation dynamics at rare arginine codons and loss of protein homeostasis in cells lacking Not4. bioRxiv 2025.12.31.695943. DOI: 10.64898/2025.12.31.695943
Ayata P, Crowley JM, Challman MF, Sahasrabuddhe V, Gratuze M, Werneburg S, Ribeiro D, Hays EC, Durán-Laforet V, Faust TE, Hwang P, Mendes Lopes F, Nikopoulou C, Buchholz S, Murphy RE, Mei T, Pimenova AA, Romero-Molina C, Garretti F, Patel TA, De Sanctis C, Ramirez Jimenez AV, Crow M, Weiss FD, Ulrich JD, Marcora E, Murray JW, Meissner F, Beyer A, Hasson D, Crary JF, Schafer DP, Holtzman DM, Goate AM, Tarakhovsky A, Schaefer A (2025) Lymphoid gene expression supports neuroprotective microglia function. Nature. Dec;648(8092):157-165. DOI: 10.1038/s41586-025-09662-z
Bilican S, Nabawi Y, Zhang WH, Petrovic D, Wehrmann M, Muñoz-García S, Koyuncu S, Vilchez D (2025) C9orf72 ALS-causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules. FEBS Lett. Sep 1. DOI: 10.1002/1873-3468.70156
Boehm V, Wallmeroth D, Wulf PO, Popp O, Teixeira Alves LG, Reinecke L, Riedel M, Wyler E, Franitza M, Becker K, Polkovnychenko K, Del Giudice S, Benlasfer N, Mertins P, Landthaler M, Gehring NH (2025) Rapid UPF1 depletion illuminates the temporal dynamics of the NMD-regulated human transcriptome. Mol Cell Sep 18, 85(18):3524-3546.e12. DOI: 10.1016/j.molcel.2025.08.015
Braun F, Mandel AM, Blomberg L, Wong MN, Chatzinikolaou G, Meyer DH, Reinelt A, Nair V, Akbar-Haase R, McCown PJ, Haas F, Chen H, Rahmatollahi M, Fermin D, Ebbestad R, Slaats GG, Bork T, Schell C, Koehler S, Brinkkoetter PT, Lindenmeyer MT, Cohen CD, Kann M, Unnersjö-Jess D, Bloch W, Sampson MG, Dollé ME, Puelles VG, Kretzler M, Garinis GA, Huber TB, Schermer B, Benzing T, Schumacher B, Kurschat CE (2025) Loss of genome maintenance is linked to mTOR complex 1 signaling and accelerates podocyte damage. JCI Insight May 20;10(12):e172370. DOI: 10.1172/jci.insight.172370
Bujarrabal-Dueso A, Garinis GA, Robbins PD, Vijg J, Schumacher B (2025) Targeting DNA damage in ageing: towards supercharging DNA repair. Nat Rev Drug Discov. Oct;24(10):785-807. DOI: 10.1038/s41573-025-01212-6
Braun F, Müller RU. Polycystic Kidney Disease: A Disorder Out of Time? (2025) J Am Soc Nephrol Mar 1;36(3):331-332. DOI: 10.1681/ASN.0000000617
Hunold P, Pizzolato G, Heramvand N, Kaiser L, Barbiera G, van Ray O, Thomas R, George J, Peifer M, Hänsel-Hertsch R (2025) DynaTag for efficient mapping of transcription factors in low-input samples and at single-cell resolution. Nat Commun 16(1):6585. DOI: 10.1038/s41467-025-61797-9
Ishikawa S, Schumacher B (2025) The Somatic Impact on Inheritance and the Germline Control of the Soma. Annu Rev Genet. Nov;59(1):91-117. DOI: 10.1146/annurev-genet-020325-040022
Koyuncu S, Dominguez-Canterla, Y, Alis, R, Salarzai N, Petrovic D, Flames N, Vilchez D (2025) The aging factor EPS8 induces disease-related protein aggregation through RAC signaling hyperactivation. Nat Aging. DOI: 10.1038/s43587-025-00943-w
Lapacz KJ, Weiss K, Mueller F, Xue Y, Poepsel S, Weith M, Bange T, Riemer J (2025) DPP8/9 processing of human AK2 unmasks an IAP binding motif. EMBO Rep 26: 2819 – 2835. DOI: 10.1038/s44319-025-00455-z
Li Q, Weiss K, Niwa F, Riemer J, Hoppe T (2025). Leucine inhibits degradation of outer mitochondrial membrane proteins to adapt mitochondrial respiration. Nat Cell Biol. DOI: 10.1038/s41556-025-01799-3
Meyer DH, Maklakov AA, Schumacher B (2025) Aging by the clock and yet without a program. Nat Aging 5, 1946–1956. DOI: 10.1038/s43587-025-00975-2
Müller JM, Altendorfer E, Freier S, Moos K, Mayer A, Tresch A (2025) Halfpipe: a tool for analyzing metabolic labeling RNA-seq data to quantify RNA half-lives. NAR Genom Bioinform 7:lqaf006, DOI: 10.1093/nargab/lqaf006
Nagel L, Grossbach J, Cappelletti V, Dörig C, Picotti P, Beyer A (2025) Analysis of Limited Proteolysis-Coupled Mass Spectrometry Data. Mol Cell Proteomics 24(4):100934. DOI: 10.1016/j.mcpro.2025.100934
Oldfield TJ, Renn R, Trentini DB (2025) Principles of ribosome-associated protein quality control during the synthesis of CFTR. bioRxiv 2025.07.11.664365. DOI: 10.1101/2025.07.11.664365
Padvitski T, Unger Avila P, Chen H, Özel C, Braun F, Kroll MK, Vossen C, Wienand P, Butt L, Unnersjö-Jess D, Göbel H, Kuppe C, Müller RU, Westermark PO, Brinkkötter PT, Schermer B, Benzing T, Wunderlich T, Kann M, Beyer A (2025) Single-Cell Resolution of Cellular Damage Illuminates Disease Progression. bioRxiv 2025.02.20.639269. DOI: 10.1101/2025.02.20.639269
Petrovic D, Perçin G, Vilchez D (2025) Shuttle and stabilize: H1.2-FUS complex in amyotrophic lateral sclerosis pathogenesis. Neural Regen Res. DOI: 10.4103/NRR.NRR-D-25-00422
Rothemann RA, Pavlenko E, Mondal M, Gerlich S, Grobushkin P, Mostert S, Racho J, Weiss K, Stobbe D, Stillger K, Lapacz K, Salscheider SL, Petrungaro C, Ehninger D, Nguyen THD, Dengjel J, Neundorf I, Bano D, Poepsel S, Riemer J (2025) Interaction with AK2A links AIFM1 to cellular energy metabolism. Mol Cell. 2025 85(13):2550-2566.e6. DOI: 10.1016/j.molcel.2025.05.036
Sakthivelu V, Schmitt A, Odenthal F, Ndoci K, Touet M, Shaib AH, Chihab A, Wani GA, Nieper P, Hartmann GG, Pintelon I, Kisis I, Boecker M, Eckert NM, Iannicelli Caiaffa M, Ibruli O, Weber J, Maresch R, Bebber CM, Chitsaz A, Lütz A, Kim Alves Carpinteiro M, Morris KM, Franchino CA, Benz J, Pérez-Revuelta L, Soriano-Campos JA, Huetzen MA, Goergens J, Jevtic M, Jahn-Kelleter HM, Zempel H, Placzek A, Hennrich AA, Conzelmann KK, Tumbrink HL, Hunold P, Isensee J, Werr L, Gaedke F, Schauss A, Minère M, Müller M, Fenselau H, Liu Y, Heimsoeth A, Gülcüler Balta GS, Walczak H, Frezza C, Jachimowicz RD, George J, Schmiel M, Brägelmann J, Hucho T, von Karstedt S, Peifer M, Annibaldi A, Hänsel-Hertsch R, Persigehl T, Grüll H, Sos ML, Reifenberger G, Fischer M, Adriaensen D, Büttner R, Sage J, Brouns I, Rad R, Thomas RK, Anstötz M, Rizzoli SO, Bergami M, Motori E, Reinhardt HC, Beleggia F (2025) Functional synapses between neurons and small cell lung cancer. Nature. 2025 Oct;646(8087):1243-1253. DOI: 10.1038/s41586-025-09434-9
Simonis A, Theobald SJ, Koch AE, Mummadavarapu R, Mudler JM, Pouikli A, Göbel U, Acton R, Winter S, Albus A, Holzmann D, Albert MC, Hallek M, Walczak H, Ulas T, Koch M, Tessarz P, Hänsel-Hertsch R, Rybniker J (2025) Persistent epigenetic memory of SARS-CoV-2 mRNA vaccination in monocyte-derived macrophages. Mol Syst Biol. 21:341-360. DOI: 10.1038/s44320-025-00093-6
Toiber D, Schumacher B (2025) Targeting Genome Stability to Mitigate Human Aging and Disease. Annu Rev Pathol. Oct 14. DOI: 10.1146/annurev-pathmechdis-042624-105942
Totska K, Barata JCVV, Sandt W, Meyer DH, Schumacher B (2025) Age Deceleration and Reversal Gene Patterns in Dauer Diapause. Aging Cell Oct 17:e70253. DOI: 10.1111/acel.70253
Weiss K, Agarkova Y, Zwosta A, Hoevel S, Himmelreich A, Shumanska M, Etich J, Poschmann G, Brachvogel B, Bogeski I, Mielenz D, Riemer J (2025) A fluorescent sensor for real-time monitoring of DPP8/9 reveals crucial roles in immunity and cancer. Life Science Alliance May 8 (8) e202403076. DOI: 10.26508/lsa.202403076
Weith M, Weiss K, Stobbe D, Riemer J (2025) The mitochondrial intermembrane space – a permanently proteostasis-challenged compartment. Biological Chemistry. DOI: 10.1515/hsz-2025-0108
Zarges C, Fieler H, Rothemann RA, Poepsel S, Jae LT, Riemer J (2025) The mitochondrial disulphide relay substrate FAM136A safeguards IMS proteostasis and cellular fitness. Redox Biol Oct 8;87:103884. DOI: 10.1016/j.redox.2025.103884
Zimmermann J, Lang L, Malo Pueyo J, Riedel M, Wahni K, Stobbe D, Lux C, Janvier S, Vertommen D, Lenhard S, Hannemann F, Castro H, Tomas AM, Herrmann JM, Salvador A, Mühlhaus T, Riemer J, Messens J, Deponte M, Morgan B (2025) Heterooligomerization drives structural plasticity of eukaryotic peroxiredoxins. bioRxiv 2025.03.03.641172. DOI: 10.1101/2025.03.03.641172
2024
Papantonis A, Antebi A, Partridge L, Beyer A (2024) Age-associated changes in transcriptional elongation and their effects on homeostasis. Trends Cell Biol. 19: S0962-8924(24)00247-2. DOI: 10.1016/j.tcb.2024.11.005
Rothemann RA, Stobbe D, Hoehne-Wiechmann MN, Murschall LM, Peker E, Knaup LK, Racho J, Habich M, Gerlich S, Lapacz KJ, Ulrich K, Riemer J (2024) Interaction with the cysteine-free protein HAX1 expands the substrate specificity and function of MIA40 beyond protein oxidation. FEBS J. 291:5506-5522. DOI: 10.1111/febs.17328
Before funding
Adamla F, Rollins J, Newsom M, Snow S, Schosserer M, Heissenberger C, Horrocks J, Rogers AN, Ignatova Z (2019) A Novel Caenorhabditis Elegans Proteinopathy Model Shows Changes in mRNA Translational Frameshifting During Aging. Cell Physiol Biochem 52: 970-983. DOI: 10.33594/000000067
Amirbeigiarab S, Kiani P, Velazquez Sanchez A, Krisp C, Kazantsev A, Fester L, Schluter H, Ignatova Z (2019) Invariable stoichiometry of ribosomal proteins in mouse brain tissues with aging. Proc Natl Acad Sci U S A 116: 22567-22572. DOI: 10.1073/pnas.1912060116
Cappelletti V, Hauser T, Piazza I, Pepelnjak M, Malinovska L, Fuhrer T, Li Y, Dorig C, Boersema P, Gillet L, Grossbach J, Dugourd A, Saez-Rodriguez J, Beyer A, Zamboni N, Caflisch A, de Souza N, Picotti P (2021) Dynamic 3D proteomes reveal protein functional alterations at high resolution in situ. Cell 184: 545-559 e522. DOI: 10.1016/j.cell.2020.12.021
Charmpi K, Chokkalingam M, Johnen R, Beyer A (2021) Optimizing network propagation for multi-omics data integration. PLoS Comput Biol 17: e1009161. DOI: 10.1371/journal.pcbi.1009161
Charmpi K, Guo T, Zhong Q, Wagner U, Sun R, Toussaint NC, Fritz CE, Yuan C, Chen H, Rupp NJ, Christiansen A, Rutishauser D, Ruschoff JH, Fankhauser C, Saba K, Poyet C, Hermanns T, Oehl K, Moore AL, Beisel C, Calzone L, Martignetti L, Zhang Q, Zhu Y, Martinez MR, Manica M, Haffner MC, Aebersold R, Wild PJ, Beyer A (2020) Convergent network effects along the axis of gene expression during prostate cancer progression. Genome Biol 21: 302. DOI: 10.1186/s13059-020-02188-9
Debès C, Papadakis A, Gronke S, Karalay O, Tain LS, Mizi A, Nakamura S, Hahn O, Weigelt C, Josipovic N, Zirkel A, Brusius I, Sofiadis K, Lamprousi M, Lu YX, Huang W, Esmaillie R, Kubacki T, Spath MR, Schermer B, Benzing T, Müller RU, Antebi A, Partridge L, Papantonis A, Beyer A (2023) Ageing-associated changes in transcriptional elongation influence longevity. Nature 616: 814-821. DOI: 10.1038/s41586-023-05922-y
Efstathiou S, Ottens F, Schutter LS, Ravanelli S, Charmpilas N, Gutschmidt A, Le Pen J, Gehring NH, Miska EA, Boucas J, Hoppe T (2022) ER-associated RNA silencing promotes ER quality control. Nat Cell Biol 24: 1714-1725. DOI: 10.1038/s41556-022-01025-4
Finger Y, Riemer J (2020) Protein import by the mitochondrial disulfide relay in higher eukaryotes. Biol Chem 401: 749-763. DOI: 10.1515/hsz-2020-0108
Fraser HC, Kuan V, Johnen R, Zwierzyna M, Hingorani AD, Beyer A, Partridge L (2022) Biological mechanisms of aging predict age-related disease co-occurrence in patients. Aging Cell 21: e13524. DOI: 10.1111/acel.13524
Grossbach J, Gillet L, Clement-Ziza M, Schmalohr CL, Schubert OT, Schutter M, Mawer JSP, Barnes CA, Bludau I, Weith M, Tessarz P, Graef M, Aebersold R, Beyer A (2022) The impact of genomic variation on protein phosphorylation states and regulatory networks. Mol Syst Biol 18: e10712. DOI: 10.15252/msb.202110712
Hänsel-Hertsch R, Simeone A, Shea A, Hui WWI, Zyner KG, Marsico G, Rueda OM, Bruna A, Martin A, Zhang X, Adhikari S, Tannahill D, Caldas C, Balasubramanian S (2020) Landscape of G-quadruplex DNA structural regions in breast cancer. Nat Genet 52: 878-883. DOI: 10.1038/s41588-020-0672-8
Johnsen M, Kubacki T, Yeroslaviz A, Spath MR, Morsdorf J, Gobel H, Bohl K, Ignarski M, Meharg C, Habermann B, Altmuller J, Beyer A, Benzing T, Schermer B, Burst V, Müller RU (2020) The Integrated RNA Landscape of Renal Preconditioning against Ischemia-Reperfusion Injury. J Am Soc Nephrol 31: 716-730. DOI: 10.1681/ASN.2019050534
Josipovic N, Ebbesen KK, Zirkel A, Danieli-Mackay A, Dieterich C, Kurian L, Hansen TB, Papantonis A (2022) circRAB3IP modulates cell proliferation by reorganizing gene expression and mRNA processing in a paracrine manner. RNA 28: 1481-1495. DOI: 10.1261/rna.079195.122
Lackner A, Sehlke R, Garmhausen M, Giuseppe Stirparo G, Huth M, Titz-Teixeira F, van der Lelij P, Ramesmayer J, Thomas HF, Ralser M, Santini L, Galimberti E, Sarov M, Stewart AF, Smith A, Beyer A, Leeb M (2021) Cooperative genetic networks drive embryonic stem cell transition from naive to formative pluripotency. EMBO J 40: e105776. DOI: 10.15252/embj.2020105776
Mackmull MT, Nagel L, Sesterhenn F, Muntel J, Grossbach J, Stalder P, Bruderer R, Reiter L, van de Berg WDJ, de Souza N, Beyer A, Picotti P (2022) Global, in situ analysis of the structural proteome in individuals with Parkinson’s disease to identify a new class of biomarker. Nat Struct Mol Biol 29: 978-989. DOI: 10.1038/s41594-022-00837-0
Mosler T, Conte F, Longo GMC, Mikicic I, Kreim N, Mockel MM, Petrosino G, Flach J, Barau J, Luke B, Roukos V, Beli P (2021) R-loop proximity proteomics identifies a role of DDX41 in transcription-associated genomic instability. Nat Commun 12: 7314. DOI: 10.1038/s41467-021-27530-y
Murschall LM, Gerhards A, MacVicar T, Peker E, Hasberg L, Wawra S, Langer T, Riemer J (2020) The C-terminal region of the oxidoreductase MIA40 stabilizes its cytosolic precursor during mitochondrial import. BMC Biol 18: 96. DOI: 10.1186/s12915-020-00824-1
Oliver KE, Rauscher R, Mijnders M, Wang W, Wolpert MJ, Maya J, Sabusap CM, Kesterson RA, Kirk KL, Rab A, Braakman I, Hong JS, Hartman JLt, Ignatova Z, Sorscher EJ (2019) Slowing ribosome velocity restores folding and function of mutant CFTR. J Clin Invest 129: 5236-5253. DOI: 10.1172/JCI124282
Papadakis A, Gyenis A, Pothof J, Hoeijmakers J, Papantonis A, Beyer A (2023) Age-associated transcriptional stress due to accelerated elongation and increased stalling of RNAPII. Nature Genetics. DOI: 10.1038/s41588-023-01601-w
Rauscher R, Bampi GB, Guevara-Ferrer M, Santos LA, Joshi D, Mark D, Strug LJ, Rommens JM, Ballmann M, Sorscher EJ, Oliver KE, Ignatova Z (2021) Positive epistasis between disease-causing missense mutations and silent polymorphism with effect on mRNA translation velocity. Proc Natl Acad Sci U S A 118: e2010612118. DOI: 10.1073/pnas.2010612118
Reverendo M, Arguello RJ, Polte C, Valecka J, Camosseto V, Auphan-Anezin N, Ignatova Z, Gatti E, Pierre P (2019) Polymerase III transcription is necessary for T cell priming by dendritic cells. Proc Natl Acad Sci U S A 116: 22721-22729. DOI: 10.1073/pnas.1904396116
Shao W, Guo T, Toussaint NC, Xue P, Wagner U, Li L, Charmpi K, Zhu Y, Wu J, Buljan M, Sun R, Rutishauser D, Hermanns T, Fankhauser CD, Poyet C, Ljubicic J, Rupp N, Ruschoff JH, Zhong Q, Beyer A, Ji J, Collins BC, Liu Y, Ratsch G, Wild PJ, Aebersold R (2019) Comparative analysis of mRNA and protein degradation in prostate tissues indicates high stability of proteins. Nat Commun 10: 2524. DOI: 10.1038/s41467-019-10513-5
Soste M, Charmpi K, Lampert F, Gerez JA, van Oostrum M, Malinovska L, Boersema PJ, Prymaczok NC, Riek R, Peter M, Vanni S, Beyer A, Picotti P (2019) Proteomics-Based Monitoring of Pathway Activity Reveals that Blocking Diacylglycerol Biosynthesis Rescues from Alpha-Synuclein Toxicity. Cell Syst 9: 309-320 e308. DOI: 10.1016/j.cels.2019.07.010
Suryo Rahmanto A, Blum CJ, Scalera C, Heidelberger JB, Mesitov M, Horn-Ghetko D, Gräf JF, Mikicic I, Hobrecht R, Orekhova A, Ostermaier M, Ebersberger S, Möckel MM, Krapoth N, Da Silva Fernandes N, Mizi A, Zhu Y, Chen JX, Choudhary C, Papantonis A, Ulrich HD, Schulman BA, König J, Beli P (2023) K6-linked ubiquitylation marks formaldehyde-induced RNA-protein crosslinks for resolution. Mol Cell. S1097-2765(23)00848-1. DOI: 10.1016/j.molcel.2023.10.011
Tain LS, Sehlke R, Meilenbrock RL, Leech T, Paulitz J, Chokkalingam M, Nagaraj N, Gronke S, Frohlich J, Atanassov I, Mann M, Beyer A, Partridge L (2021) Tissue-specific modulation of gene expression in response to lowered insulin signalling in Drosophila. Elife 10:e67275. DOI: 10.7554/eLife.67275
Tameire F, Verginadis, II, Leli NM, Polte C, Conn CS, Ojha R, Salas Salinas C, Chinga F, Monroy AM, Fu W, Wang P, Kossenkov A, Ye J, Amaravadi RK, Ignatova Z, Fuchs SY, Diehl JA, Ruggero D, Koumenis C (2019) ATF4 couples MYC-dependent translational activity to bioenergetic demands during tumour progression. Nat Cell Biol 21: 889-899. DOI: 10.1038/s41556-019-0347-9
Tognetti M, Gabor A, Yang M, Cappelletti V, Windhager J, Rueda OM, Charmpi K, Esmaeilishirazifard E, Bruna A, de Souza N, Caldas C, Beyer A, Picotti P, Saez-Rodriguez J, Bodenmiller B (2021) Deciphering the signaling network of breast cancer improves drug sensitivity prediction. Cell Syst 12: 401-418 e412. DOI: 10.1016/j.cels.2021.04.002
Trentini DB, Pecoraro M, Tiwary S, Cox J, Mann M, Hipp MS, Hartl FU (2020) Role for ribosome-associated quality control in sampling proteins for MHC class I-mediated antigen presentation. Proc Natl Acad Sci U S A 117: 4099-4108. DOI: 10.1073/pnas.1914401117
Vijg J, Schumacher B, Abakir A, Antonov M, Bradley C, Cagan A, Church G, Gladyshev VN, Gorbunova V, Maslov AY, Reik W, Sharifi S, Suh Y, Walsh K (2023) Mitigating age-related somatic mutation burden. Trends Mol Med 29: 530-540. DOI: 10.1016/j.molmed.2023.04.002
Wang S, Meyer DH, Schumacher B (2020) H3K4me2 regulates the recovery of protein biosynthesis and homeostasis following DNA damage. Nat Struct Mol Biol 27: 1165-1177. DOI: 10.1038/s41594-020-00513-1
Weith M, Grossbach J, Clement-Ziza M, Gillet L, Rodriguez-Lopez M, Marguerat S, Workman CT, Picotti P, Bahler J, Aebersold R, Beyer A (2023) Genetic effects on molecular network states explain complex traits. Mol Syst Biol 19: e11493. DOI: 10.15252/msb.202211493
Zuko A, Mallik M, Thompson R, Spaulding EL, Wienand AR, Been M, Tadenev ALD, van Bakel N, Sijlmans C, Santos LA, Bussmann J, Catinozzi M, Das S, Kulshrestha D, Burgess RW, Ignatova Z, Storkebaum E (2021) tRNA overexpression rescues peripheral neuropathy caused by mutations in tRNA synthetase. Science 373: 1161-1166. DOI: 10.1126/science.abb3356